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Table 1 Common Causes and Classification of Angioedema

From: Angioedema

1. Allergic/anaphylaxis

Foods, for example, peanuts, shellfish, milk, eggs, tree nuts Drugs, especially penicillin and sulfa drugs and their derivatives Venoms, stinging insects (bees, yellow jacket, hornet, wasp) and fire ants

2. Associated with physical processes, for example, cold urticaria, cholinergic urticaria, vibratory angioedema, exercise-induced anaphylaxis

3. Associated with chronic urticaria, either autoimmune or idiopathic

4. Vasculitis, idiopathic urticarial vasculitis, and urticaria associated with connective tissue diseases

5. Anaphylactoid, radiocontrast agents

6. NSAID induced

7. C1 INH deficiency (hereditary, acquired)

8. ACE inhibitors

9. Idiopathic angioedema

   a. Histamine, dependent (histaminergic)

   b. Histamine, independent (nonhistaminergic)